Amiodarone-Induced Thyrotoxicosis

 

  Type 1 Type 2
pre-existing thyroid disease
Yes No
Ultrasound pattern
diffuse or nodular gointer heterogeneous
Doppler sonography
normal or increased flow decreased flow
24h radioiodine uptake
normal or elevated (typically >5%/24h) very low (typically <2%/24h)
thyroid autoantibodies
may be present usually absent
response to steroids
No Usually Yes

From Conen, et al, JACC Vol 49, No. 24, 2007 June 19, 2350-5